I was able to get it running, after awhile.
Setup wise, you're going to be running an ST4 cable from your guider to the Star Adventurer as it has no goto control.
The first thing I did was set up a profile with 'Telescope Simulator' for a mount. I use a QHY 5-II-L as a guide camera, so I set QHYCCD as the Guider. I also have a QHY 294C for an imaging camera, so CCD got set to QHYCCD as well.
Once you've loaded the profile, head over first to the Mount Module.
Why, you might ask, given that it's a simulated mount? Because on mine it happened to be set to Auto Park at 1:00 in the morning, and when that happens any guiding underway gets shut down. So turn that off and turn off any meridian flipping too. Also make sure it's UnParked and Tracking is On.
For Alignment, you can use your guide camera+guide scope, or, if you have an imaging camera that is INDI-compatible, you can use that too. Start the process in the KStars sky window by selecting the object and telling the Telescope Simulator to go to it. Meanwhile, in the real world, move your Star Adventurer to that area of the sky. Once the Telescope Simulator is on the target and you've moved the SA, go to the Alignment Module and set the Solver Action to Sync. Having made sure you've got the right combination of scope and CCD, you can then carry out a 'Capture & Solve'. It'll then tell you how far off you are, and back in the sky window it will show you how far out you are. Then readjust the SA, repeat the Alignment, and so on.
Now move on to the Guider Module. This is where I ended up wasting a great deal of time. The first thing to do here is to make sure the Guider is set to the correct device and then make sure 'Via' is set to the guide camera and not 'Telescope Simulator'... this is because you're using an ST-4 cable to issue commands to the mount. Next, since the Star Adventurer has no declination motor, *OBVIOUSLY* it can't control declination. So one would think that simply unchecking 'DEC' under Directions would suffice. No, sadly... every time I told it to start guiding it would attempt to start drifting Dec after RA in the calibration and eventually fail. So what you also have to do is go to 'Options' in the lower righthand corner and uncheck "Two Axis" on the Calibration Pane. After that it will calibrate on RA only and start guiding.
Prior to Aligning, you could probably do an Ekos polar alignment with a manual slew. I haven't tried it since you can get decently accurate polar alignment for < 400 mm with the SA's own polar finder.