Yes, for me this is clear now.
Maybe a note can be added somewhere in the INDI client documentation, maybe in the Standard Property page, that changing the binning can change the CCD_FRAME value, despite it is unbinned pxiel.
Thomas, the stable ppa is already without the change that reduce the maximum frame size in binning 1x1, so you can install this version now.
You can check the frame size is 4656x3520 after connection to be sure this is this version.
AIUI this camera hardware requires that the image width (and start X?) is a multiple of 8 pixels, so widths of 8, 16, 24, 32 etc. If the user asks for 20 then could the camera be asked for the next multiple up, so 24 pixels, then the driver software extracts the the required data from the larger frame supplied by the camera?
I understand this is more complex for the driver but the client would get what they asked for.