I use persistent serial port mapping for my all my serial devices with virtually no problem (e.g. /dev/mount, /dev/filterwheel, /dev/focuser,...), except that once in a while a device connects as /dev/bus/usb/00x/00y instead of /dev/ttyUSBz and the port mapping doesn't work. This seem to happen when I disconnect/reconnect the device or if I connect it after the system as booted. As I ideally do not want to reboot to correct the problem, I wonder if there is a reason/solution/work-around to this issue.