Herrhausen, thanks for the suggestion
The solution is UNBELIEVABLE it all works if you connect the camera to the USB2 rather than USB3.
The threads quoted by starman345 point to a problem Unix Core problem, maybe only with the version running on Rock64
I assume that as I did an sudo apt update / sudo apt upgrade I have got the latest version. I am now running Armbian 5.3 but the problem persists.

It looks like it has to do with file size, the ASI294 generates an 11.7MB file which is twice as large as my ASI178MC. For smaller files including 8 bit USB3 works fine.
Just to check I set up a job to capture 120 x 5 sec 16 bit exposures with only a 1 sec delay and it works fine.

The shame is I ditched my old RPI3 to get the Rock64Pro for the USB3 port. It is however much faster on plate solving and other tasks
I wonder if any of the RPI4 early users are getting any problems with USB3 and large file size cameras?

At least it works now.
Thanks for the help!
Max

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