Running ASI1600mm, ASI120mm mini, EFW, EAF, building from git on RPI4. No issues (anymore).
I did have an issue with the ASI1600mm where it would fail to capture, and the image from the ASI120mm would occationally pop up in the preview instead.
Deleted xml-files from .indi, and set everything up from scratch again. After deleting the xml-files, I saw that the ekos driver setting for both ASI120mm and ASI1600mm were both set to main scope. I set ASI120mm to guide scope, and everything were working again. Not in front of kstars at the moment, so tick boxes could have different names.