Sorry for not replying for a long time, I was in contact with iOptron support. But I found the solution for the problem here in the forum:
indilib.org/forum/mounts/8815-ioptron-ge...-issue.html?start=36 
The problem is that the USB on the mount draws too much current. I have now passed the USB cable from the iOptron GEM45 through my Omegon Pro camera and then to the Raspi and now it works. 
Thanks for your help

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Have tried all available and now again checked the firmware for updates. Unfortunately it still does not work
 



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As far as I can see it is the latest firmware:
HC V2 210105
Main 210106
RA/DEC 210105
The stellaremate OS is 1.5.8
I cannot update it to 1.5.9, I have run the update process several times with the integrated updater and the version is still the same

Thanks, Andreas

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Hello,
After several nights of trying to get the guiding to work (Touptec via Touptec), which was not successful, I wanted to try Touptec via Gem45.
I have connected the RS to USB cable to the HC
But I always get a timeout error. I have now tried every option. It recognizes the adapter, but somehow it doesn't want to.
Can it be that it is not working with the Raspberry 3?
Thanks for help

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