The pinout of the 40 pin header is the same, so the hardware is compatible. However, the driver will need to be modified to support the Orange Pi, because every brand of single board computer has a different method of controlling the GPIO pins on the header.

To get it to work would require some back and forth between me and someone who actually owns an Orange Pi (possibly you) doing testing, etc. to get it to work. Overall it's probably a worthwhile endeavor, since the Orange Pi is a popular alternative to Raspberry Pi.

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