I'm using QHY163 and old QHY5 (first version) on a single INDI driver and they work (mostly). Unfortunately this setup doesn't work on RaspberryPi 3 or 4. I only managed to get it working on intel based laptop. Please note I didn't yet try to use both cameras at the same time. I can only confirm that I can connect to both from KStars and take a single frame from each.