Booting and running from HDD/SSD is not astroberry specific. If you configure your system to boot/run from external drive astroberry will be fine.
kalda wrote: is it possible to install Astroberry Server2 on hdd/sdd or only to SD? (Raspberry Pi4)
If you mean whether virtual gps will work on others hardware, the answer is yes, it should work. Regarding whole Astroberry Server the answer is no, it is designed to work on raspberry only.
tkottary wrote: Will this work on Tinkerboard (armbian os) & Nvidia Jetson Nano( ubuntu ) ?